This remedy has been used for chills and fever, characterized by rush of blood to the head, vertigo prickly sensation in the face which is hot and flushed; chill, with darting pain in the back and limbs, heat with headache and flushed face, perspiration not profuse; rarely any thirst; during the apyrexia, disordered liver, jaundice, headache, constipation, etc; especially adapted to chronic cases.