ANTIPYRINUM
Synonyms: Antipyrine; Phenazone; 2,3-dimethyl-l-phenyl-3-pyrazoline-5-one
THE ESSENTIAL FEATURES
Antipyrine is a remedy that is required in allergic conditions which manifest primarily in the skin or the upper respiratory tract. This remedy should be considered when a case resembles, but is not completely consistent with, Belladonna. It can also resemble Ailanthus, Pulsatilla, or Chloralum, but none of those options will seem satisfactory.
This remedy will be indicated in cases which, present with a history of urticaria or angioneurotic edema which appears suddenly and disappears suddenly ( like Belladonna ), associated with intense itching and an internal coldness, as if there were ice inside the body. The remedy seems to lower the temperature of the body, depress the respiration and circulation, and produce at the same time profuse sweat. The kidneys may be involved, and there may be a general swelling of the body. The face will be red and swollen, edematous, puffy. The symptomatology in general will look like Belladonna or Apis , but because of the internal coldness, the differential diagnosis favors Antipyrine.
Another allergic condition for which Antipyrine may be indicated is hay fever characterized by violent and continuous sneezing – thirty to fifty times in a row – during which the eyes water and mucus runs from the nose. The breathing is also affected, eventuating in dyspnea which is worse on lying down, with violent coughing, expectoration of much mucus and profuse sweat. Itching and burning of the palate of the mouth occurs. Again, the face is red and swollen, especially the eyelids, creating the impression that the case is one of Apis , but there is not the expected aggravation from heat. To the contrary, there is a sensitivity to cold and profuse sweating whereas in Apis and Belladonna dry heat is prevalent. Also seen is fever after rising in the morning, soon dissipating thereafter.
Deep congestion of the frontal sinuses occurs, and a headache may develop that makes him run up and down the room screaming.When in such a state, the patient will fear that he may lose his mind if