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Materia Medica Viva Volume 3 – page 696

skin was smooth and adherent, and upon one point of this surface appeared a violet spot, whcih indicated the commencement of Hay’s fungus haematodes, one of the most distinctive signs of the passage of scirrhus into cancerous degeneration.
Her general health was good; at distant intervals, however, she experienced lancinating pains in the tumour. She took asterias 18, a drop in eight days, and the dose was renewed at the expiration of similar periods for several months. The gland had then lost two-thirds of its volume, but the varicose spot showed some grayish points, had become more decided in colour, more extended in surface, had broken, and from time to time discharged some blood. The excoriation did not, however, resemble the usual fungus haematodes, as the bottom was smooth and formed of a tissue of varicose capillaries, while she felt no pain in it, and had no longer any general symptoms. The usual sequel of a bloody discharge, the secretion of an ichorous fetid fluid, did not take place, and this circumstance, in connection with the great diminution of the tumour, leads me to hope there will be no relapse.
A lady of a nervous sanguineous temperament, aged 48, had suffered more or less during her whole menstrual life. A long time ago she had had an engorgement of the cervix uteri, which, though finally cured, had caused fears of its ending in a malignant disease; from that time she had never been perfectly well. A year since, a swelling came on in the right breast, involving the whole mammary gland; it was hard, unsymmetrical, and was attached to the nipple, which was buried in the tumour. She experienced lancinating pains in it, shooting as far as the spine, at about the position of the fourth dorsal vertebra, the region of which was so painful that the slightest pressure was intolerable. In the track of this pain, a hard and knotty cord soon formed and rendered the whole space between the breast and the spinal column equally sensitive. On the external side of the tumour, which increased daily in size, a fungus haematodes formed as in the previous cases, and soon formed a projection of about two centimetres. It soon opened, giving vent to a copious haemorrhage, followed some days afterwards by a fetid ichor. The engorgement extended to the axillary glands; the disease rapidly advanced, and asterias was employed, but without effect. We may, perhaps, get a glimpse of the reason of this inertness, if we remember that in the pathogenesis of asterias, the action of the remedy seems to be concentrated upon the left side of the body, and that in the two cases of which I have given a rapid review, and in which it was employed with such decided results, the affection was also upon the left side, while in the present case it was wholly on the right.
Case 6. – The first ideas I had about the curative action of asterias referred to its probable influence upon epilepsy, a notion to which the celebrated Cotugno had lent some credit. But the seat and the causes of this disease are so varied, while its phenomena remain nearly the same, that it will, probably, long remain one of those which will be treated by the practitioner without result.
A young girl of 22, of a delicate, lymphatic and very irritable temperament, complained, when twelve years old, of headache. It was. a violent pressure upon the anterior lobes of the brain, extending even beneath the eyes, and one day became so severe that the patient, when seated at table, fell forward and remained for some minutes unconscious; her face was pale and her jaws set. Such was her first attack, after which she experienced great debility, with a sense of distress in the epigastrium.