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Materia Medica Viva – Volume 2 page 414

the condition persists. There is an element of hysteria in Antipyrine and a definite overexcitement with continuous crying. The congestion is such that the patient feels numb in his mind, stupid and idiotic; he cannot remember anything and actually thinks he is going to go crazy – fear of impending insanity. The characteristic here is not that he is afraid that he is insane, but that he will become so in the future. If the headache is extremely severe, he may have hallucinations of sight and hearing.
There is another keynote of this remedy that will be seen primarily in cases of gastroenteritis or in stomach problems or colitis. There is a sensation as if the contents of the thorax and abdomen were being forced upwards. There is a similar feeling of the right testicle being drawn up into the abdomen.
This remedy, as others which have been presented, meets a very unique set of conditions which cannot be treated with any other remedy. Nevertheless, most of us miss these little remedies when the cases first present to us, and we mistakenly subject our patients to a sequence of similar, but inexact prescriptions. In cases calling for Antipyrine, we usually employ several other remedies in succession, such as Belladonna, Apis, Pulsatilla, etc.
Consider, for instance, a patient who complains of fever in the morning after rising. He may need Calcarea carbonica, which has this symptom, but he also might need Antipyrine if the symptoms agree. Calcarea has the fear of insanity as well. However, the internal icy coldness that our patient complains of is not met with Calcarea, even though Calcarea feels the cold and is aggravated by it.
One cannot stress enough the importance of minute details and nuances of symptomatology. For example, there is a difference between the statements "I feel I am crazy," "I fear I will become crazy any minute," and "I fear that if this condition continues I will go crazy." Antipyrine has for the most part this last feeling, Calcarea the first. I realise that these are difficult and very subtle points of differentiation, but as one considers these fine distinctions and then re-examines the entire case, it will become apparent that the case displays the characteristic pathology of Antipyrine rather than Calcarea.
I acknowledge that the most difficult part of our science is the differential diagnosis of remedies, but all sciences have their innate difficulties which demand special dedication before they can be mastered. In our science the greatest possible dedication and enthusiasm is required.