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Materia Medica Viva Volume 10 – page 2201

‘Frequent sharp, darting pains from one part of the body to another’ is one of the general guiding symptoms of the remedy.
Hale concludes: ‘If you find in any painful affection of the abdomen, stomach, uterus, or even the heart or head, that the pain, though constant, is aggravated in paroxysms; is attended by spasmodic symptoms (vomiting, cramps), or sympathetic pain in distant parts of the body, you can prescribe Dioscorea with advantage. For instance, it has cured headache, remittent, paroxysmal, attended by spasmodic pain in abdomen, facial neuralgia; cardialgia, spas- modic and flatulent colic, painful tenesmus; spasms of the bladder and uterus; spasm of the gall-ducts; sciatic neuralgia, the pain running from the hip to the ankles’.
Especially in abdominal pain, the modalities of Dioscorea are significant. Dioscorea pain is usually ameliorated by stretching and making an arch, by rising up, by assuming a straight and upright position, by standing erect, sitting erect, or lying flat and straight. Even bending backwards will often relieve the abdominal pain. ‘Sharp pain at epigastrium, aggravated by stooping, relieved by standing erect’ (from the proving). Relief is only possible by stretching the body and walking about in an extremely upright position. The amelioration by stretching and erect posture is a guiding symptom of Dioscorea. In some cases, not even the slightest pressure upon the abdomen is tolerated.
Another general modality is an amelioration of all symptoms by motion, especially by continued motion in the open air. When the patient is lying in bed, he is frequently ameliorated by rising from the bed, stretching, and walking about the room. This is true for abdominal pain and nervousness, but also in the case of rheumatic pain. ‘Hands and fingers ache, and are very stiff; closing the hands is very painful; ankles, feet and toes are also very stiff, and ache constantly. After exercising two hours hands and feet felt