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The Celle Seminars – Page 193

This disorder is transmitted by x-linked genes.
The clinical symptoms are the following: pains, skin lesions, cardiac-cerebral-renal manifestations which include myocardial ischemia and infarction, heart failure, cardiac enlargement. From the kidneys: proteinuria and other signs of renal impairment with gradual deterioration of renal function. Development of acetonemia in middle-age. Ocular features: lesions and lenticular changes have been described; conjunctiva and retinal vascular relations are common and represent part of the diffuse system involvement of vessels. Other clinical features: lymphedema of the legs may be present in adulthood, and priapism has also been reported; episodic diarrhea; chronic bronchitis was described in one case; anemia is probably due to the decreased red blood cells survival; muscle-skeletal system derangements.
(G.V.): This is a rather severe disease that we are dealing with here. The most important thing for you to keep in mind is that this disease is caused by a lack of the A-galactosidase. I’ve never seen a case like this before; I don’t have any experience with such diseases. What can Homeopathy do when faced with a genetic defect of this type? We’ll have to wait and see. So far, we know from the information he gave that he is worse from exertion and heat and better when bathing in cold water. Immediately certain remedies with this range of symptomatology come to mind. The first remedy we would think of in this case is Pulsatilla. We go away from ‘exertion aggravates’ of the Calcareas. The Calcareas are also very easily irritated by exertion, especially Calcarea carbonica, but we would have to abandon this remedy because amelioration with cold does not fit Calcarea carbonica. The symptom physical exertion, worse also indicates another one of the Calcareas – Calcarea Sulphurica – very strongly, with Pulsatilla on the second degree. He says that when his body temperature rises even a little the symptomatology becomes very severe. This leads us to the possibility of another remedy, one which is very much better with cold applications: Ledum.