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Materia Medica Viva – Volume 2 page 463

3. J.H.Clarke reports that hydrocephalus has been cured with it: in one case "the child lying, with constant involuntary motion of one arm and leg", in another case "paralysis of left side; one eye motionless, one rolling." Also, three cases of neuralgia of the right side – groin, hip, and in one case the region of right kidney – have been cured with this remedy. All were violent, extorting cries. In one case the pain set in very suddenly and the slightest jar aggravated.
J.H.Clarke, reported in his Dictionary of Practical Materia Medica, Vol. I, p. 148.
4. A young woman complained of edema of the legs and ankles first only at menses and now continuous for several months. She was chilly and craved warmth; always thirsty; no perspiration; history of illness prior onset of edematus condition which was becoming progressively persistent.
Apocynum200, one dose, controlled this edema for many months. Several doses were given to have on hand if edema recuned, and report when used. A couple of days after the first dose she reported profuse excessive urination and the edema of legs disappeared and had not returned up to about 6 months of follow-up. She also seemed in brighter spirits (a subjective observation)! Everyone was pleased, especially the young woman with the recovery of her beautiful legs. Here too, because of the history of illness prior onset of edema, I felt a constitutional remedy was indicated but this was not to be, for the Apocynum had removed all her complaints.
Journal of Am. Inst, of Horn. ,Vol.71, No. 3, Sept 1978, p.184.