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Materia Medica Viva Volume 1 – Page 97

ADRENALIN
Adrenalin is also called Epinephrine. It is a sarcode and it is obtained as an extract from the adrenal or suprarenal glands. In Homeopathy we use the tincture or trituration. Practitioners should take special care when using this extract, to find out the exact composition origin of the remedy used by the pharmacy.
PHYSIOLOGICAL ACTION
Adrenalin or epinephrine is a 3,4-dihydroxy-a(methylaminomethyl) benzyl alcohol. It is a catecholamine and the chief neurohormone or neurotransmitter of the adrenal medulla. It has a sympathomimetic action on adrenergic a and b receptors resulting in increased heart rate and contraction, vasoconstriction or vasodilation, relaxation of bronchiolar and intestinal smooth muscle while corresponding sphincters are stimulated, lipolysis, etc. Epinephrine and generally catecholamines increase metabolic rate, and stimulate the breakdown of stored fuel with the production of substrate for local consumption; for example glycogenolysis in the heart. It also contributes to the regulation of the volume and composition of extracellular fluid, promoting cellular uptake of potassium in the renal tubule. Epinephrine along with the other catecholamines – norepinephrine and dopamine, also influence the secretion of renin, insulin, glucagon, calcitonin, parathormone and possibly testosterone.
In the viscera, especially the stomach and intestines and less so in the uterus and skin, Adrenalin causes constriction of the peripheral arterioles resulting in a rise in blood pressure. It also increases glandular activity, promotes glycosuria, depresses the respiratory center, and promotes contraction of muscular tissue of the eye, uterus and vagina while relaxing the muscular tissue of the stomach, intestines and bladder.
In classical medicine it is used in the treatment of bronchial asthma [status asthmaticus], acute allergic disorders, open-angle glaucoma and heart block and as a local vasoconstrictor.
THE ESSENTIAL FEATURES
This remedy – when properly proved and understood – will, 1 believe, become one of our major assets in combating contemporary diseases such as hypertension, diabetes, paroxysmal tachycardia with anxiety, arteriosclerosis and in general diseases that have come about because of the stresses of contemporary life. It is a remedy from which we could learn a lot, should we be able to test it in high potencies on animals or