The In-Vitro Evidence for an Effect of High Homeopathic Potencies–a Systematic Review of the Literature.
IACH - Prof. G. Vithoulkas
The In-Vitro Evidence for an Effect of High Homeopathic Potencies–a Systematic Review of the Literature.
  • Author(s)

    Witt CM, Bluth M, Albrecht H, Weisshuhn TE, Baumgartner S, Willich SN

    Journal

    Complementary Therapies in Medicine. 2007 Jun;15(2):128-38.

    Notes

    This was essentially a meta-analysis of all of the in-vitro studies that have attempted to demonstrate a homeopathic effect to date, carried out by Professor Claudia Witt and colleagues at the Department of Epidemiology and Health Economics, Charité University Medical Center in Berlin, Germany. The aim here was to search all appropriate databases for relevant studies, determine which studies met the quality criteria set by the researchers, and then to determine which, if any of these, exhibited a statistically significant effect in this area. 67 papers were identified that met the quality criteria and of these, 73% found that an effect from high potencies can be demonstrated. The majority of these studies involved the effects of potentised substances on basophils. Replication of some of these studies has been carried out.

     

    Abstract

    OBJECTIVE:

    Systematic assessment of the in vitro research on high potency effects.

    METHOD:

    Publications of experiments were collected through databases, experts, previous reviews, citation tracking.

    INCLUSION CRITERIA:

    stepwise agitated dilutions <10(-23); cells or molecules from human or animal. Experiments were assessed with the modified SAPEH score.

    RESULTS:

    From 75 publications, 67 experiments (1/3 of them replications) were evaluated. Nearly 3/4 of them found a high potency effect, and 2/3 of those 18 that scored 6 points or more and controlled contamination. Nearly 3/4 of all replications were positive. Design and experimental models of the reviewed experiments were inhomogenous, most were performed on basophiles.

    CONCLUSIONS:

    Even experiments with a high methodological standard could demonstrate an effect of high potencies. No positive result was stable enough to be reproduced by all investigators. A general adoption of succussed controls, randomization and blinding would strengthen the evidence of future experiments.

    Category: In Vitro Studies

    External url

    https://www.ncbi.nlm.nih.gov/pubmed/17544864

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