Evaluating Complementary Therapies for Canine Osteoarthritis—Part II: A Homeopathic Combination Preparation (Zeel).
IACH - Prof. G. Vithoulkas
Evaluating Complementary Therapies for Canine Osteoarthritis—Part II: A Homeopathic Combination Preparation (Zeel).
  • Author(s)

    Hielm-Bjorkman A, Tulamo RM, Salonen H, Raekallio M.

    Journal

    Evid Based Complement Alternat Medorrhinum 2009 Dec;6(4):465-71

    Notes

     The Faculty of Medicine at the University of Helsinki was the setting for this trial, which involved an investigation of the anti-osteoarthritic capacity of Zeel, a combination of homeopathically potentised ingredients. Using a randomized, double-blind, placebo-controlled protocol, 44 dogs suffering from osteoarthritis were randomly allocated to receive either Zeel or one of two versions of a placebo control. All dogs received these materials for 8 weeks and were examined every 4 weeks after an initial assessment which consisted of mobility, force-plate variables, owner-evaluated chronic pain and pain and mobility index, as well as the intake of non-steroidal anti-inflammatory drugs. The results collected showed that when compared to controls, the intake of Zeel was associated with a statistically significant reduction in osteoarthritic pain.

     

    Abstract

    A homeopathic combination preparation (HCP) for canine osteoarthritic pain was evaluated in a randomized, double-controlled and double-blinded clinical trial. Forty-four dogs with osteoarthritis (OA) that were randomly allocated into one of three groups completed the study. All dogs were fed test products or placebo for 8 weeks. The dogs were evaluated at the clinic four times, with 4-week intervals. Six different variables were assessed: veterinary-assessed mobility, two force plate variables, an owner-evaluated chronic pain index and pain and locomotion visual analogue scales (VASs). Intake of extra non-steroidal anti-inflammatory drugs was also evaluated. A Chi-squared test and a Mann–Whitney test were used to determine significant improvement between groups. When changed into dichotomous responses of ‘improved’ or ‘not improved’ three out of the six variables showed a significant difference (P = 0.016, P = 0.008, P = 0.039) in improved dogs per group, between the HCP group and the placebo group. The odds ratios were over one for the same variables. As extent of improvement in the variables from start to end of treatment, the HCP product was significantly more improved in four (P = 0.015, P = 0.028, P = 0.049, P = 0.020) of the six variables, compared with the placebo. Our results indicated that the HCP Zeel® was beneficial in alleviating chronic orthopedic pain in dogs although it was not as effective as carprofen.

    Category: Animal Studies

    External url

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781775/

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